To determine whether an individual cancer was prone to metastasize.

Coussens and her colleagues found that some cancers subvert macrophages macrophages the the killer T – cells and keep them away from tumors.A rationally designed STUDYthis this revolution in tumor biopsies the team of 677 people with breast cancer examined obvious. Made theme profile on the relative abundance of three immune cells obtained in the tumors – the killer T cell, macrophage, and other immune cells helper T helper T cell – accurately predicted overall survival of the disease, to determine whether an individual cancer was prone to metastasize, and predicted whether to deal with recurring once. The tumors that worse tended to have less of the treatment killer T cells in them.

The body is filled with immune cells detect and destroy tumors, but these cells often prove completely ineffective in controlling cancer. In addition, certain types of cancers actually co-opt immune cells and use them to help tumors grow.. Why the BODY is immune to cancer?breast cancer continue to be a major health problem in the United States, and the National Cancer Institute estimates, more than 200,000 Americans with the disease are diagnosed each the second leading cause the second leading cause of cancer death in American women, claiming more than 40,000 lives alone in 2009.The program is launched in April 2008 as the first 100 scientists used by the NIHR leader health and Welfare research selected.

Being Turning major breakthroughs in life-saving treatments and cure the big challenge Applied Health Research Advances through the sharing of knowledge and know-how achieved, and with strong leadership, to NIHR director senior investigator of the program encourages and supports. Notes1 complete list of Senior Investigator appointments may be consulted here.