ON is a small molecule that base pairs of DNA base pairs of DNA in the minor groove.

ON is a small molecule that base pairs of DNA base pairs of DNA in the minor groove, Induction of DNA cross links and is currently in clinical development in refractory solid tumors and hematological malignancies under a CRADA with support of the Division of Cancer Treatment and Diagnosis by NIH U01 CA099177 and M01 RR00095 grants. The agent belongs to an entirely new class of DNA minor groove binding agent designed to detect the induced DNA damage by minimized the DNA repair machinery and encouraging clinical results have in refractory solid tumors cancer at the last ASCO meeting reported.

Further analysis will be conducted to the full results, including the secondary endpoints, to investigate. The sodium oxybate Phase III clinical program also includes a second randomized, double-blind, placebo-controlled trial at locations in at sites in the U.S. And Europe. More than 90 % of the subjects have included in this second phase III trial. Jazz Pharmaceuticals anticipates submitting a New Drug Application for sodium oxybate to the U.S. Food and Drug Administration by the end of 2009. UCB expects to file in the EU shortly after.. Only primary efficacy and safety data are tested at this time.By courtesy of It can use the whole Kaiser Daily Health Policy Report show, search the archives or sign up for email notification for the Emperor Daily Health policy coverage strongly supported kaiser network. A free service from of The Henry J. Released. Henry J. Kaiser Family foundatio 2005 Advisory Board Company and Kaiser Family Foundation. All Rights Reserved part.

J Anthem mother company WellPoint, said the company strongly disagrees from allegations and plant to defend herself. Anthem has available more than once Advocate directly with the city law for more information on Anthem resignation processes offer, said Shannon Troughton of well point. To date, the city attorney be declined any those tenders, and we are disappointed with by his actions today, since at our attempts to meet with him, she added..