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Forward-Looking StatementsCertain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. Such forward-looking statements include statements relating to the therapeutic applications of CR845 and about Cara strategy, technology, preclinical and clinical programs and the ability to identify and develop, as well as other statements that are not historical facts. Actual events or results may differ materially from expectations Cara. Among the factors that could cause actual results to differ materially from the forward , but are not, but are not limited to, the timing, success and cost of Cara limited research and clinical studies and Cara ability to obtain additional financing. These statements represent Cara judgment as of the date of this news release. Cara disclaims any intention or obligation to update these forward-looking statements.

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