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Alnylam seeks CTA clearance to initiate ALN-PCS Phase I clinical trial for severe hypercholesterolemia Alnylam Pharmaceuticals, Inc. , a leading RNAi therapeutics business, announced today that it has filed a Clinical Trial Software with the Medicines and Healthcare items Regulatory Agency to initiate a Stage I clinical trial with ALN-PCS, an RNAi therapeutic for the treating severe hypercholesterolemia. Upon receiving clearance of the CTA, Alnylam plans to initiate the Stage I trial and expects to provide initial safety, tolerability, and scientific activity data from this scholarly study by the finish of this year dostinex use click here . Moreover, we are excited about the prospect of ALN-PCS to make a direct effect in the treating severe hypercholesterolemia as this RNAi therapeutic targets both intracellular and extracellular PCSK9, a target validated by individual genetics that is known to play a central function in LDL cholesterol rate of metabolism,’ said Akshay K.

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Alpha Pro Tech’s net income increases 118.6 percent to $905,000 in third quarter 2013 Alpha Pro Tech, Ltd. , a leading manufacturer of products designed to protect people, products and environments, including disposable defensive building and apparel items, announced financial outcomes for the three and nine a few months finished September 30 today, 2013. Consolidated sales for the 2013 third quarter increased 18.2 percent to $12.7 million from $10.7 million for the comparable quarter of 2012. September 30 Building Supply segment sales for the 90 days ended, 2013 increased by 41 percent to a record $8.2 million, compared to $5.8 million for the same amount of 2012.